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Table 4 Median biochemical response to their first course of 13-cis-retinoic acid

From: 13-cis-retinoic acid re-differentiation therapy and recombinant human thyrotropin-aided radioiodine treatment of non-Functional metastatic thyroid cancer: a single-center, 53-patient phase 2 study

Analyte (n: number of evaluated patients)

Median

P, Day 42 vs. Day 1 Serum Concentrations

 

Pre-treatment (Day 1)

Day 42

Absolute (Relative) Difference,

Day 42 vs. Day 1

 

Total cholesterol, mg/dL (n = 46)

208

220

20.5 (9.6%)

<0,05

Triglycerides, mg/dL (n = 41)

114

171

75.8 (54.1%)

<0,05

Aspartate aminotransferase, U/L (n = 42)

20

25

3.1 (13.4%)

<0,05

Alanine aminotransferase, U/L (n = 43)

18

23

2.7 (12.0%)

<0,05