In contrast to matrix metalloproteinases, serum adiponectin concentrations increase after radioiodine treatment of thyrotoxicosis

Table 1 Descriptive statistics for the measurement results “before” and “ after” thiamazole therapy (Group 1; n=15)

	mean	median	SD	min	max	p-value
MMP-2 – before [ng/ml]	671.7	668.0	73.4	551.8	824.0	0.78
MMP-2 – after [ng/ml]	616.7	612.0	76.2	446.0	733.0	0.78
MMP-9- before [ng/ml]	928.0	880.0	464.8	300.0	1960.0	0.93
MMP-9 – after [ng/ml]	1238.7	1200.0	421.7	650.0	1890.0	0.93
TIMP1- before [ng/ml]	374.7	390.0	109.8	70.0	500.0	0.83
TIMP1- after [ng/ml]	382.0	370.0	70.8	280.0	510.0	0.83
TIMP2- before [ng/ml]	207.7	205.0	42.8	150.0	280.0	0.18
TIMP2- after [ng/ml]	179.7	185.0	38.2	105.0	245.0	0.18
Adiponectin – before [ng/ml]	30807	31190	12996	8450	52090	0.36
Adiponectin – after [ng/ml]	32755	34490	16638	2800	56100	0.36
TSH - before [mIU/l]*	0.007	0.005	0.003	0.005	0.01	*0.013*
TSH – after [mIU/l]	1.064	0.03	1.74	0.0	5.77	*0.013*
FT ₃ – before [pg/ml]*	8.74	7.53	4.79	4.02	16.5	*0.0010*
FT ₃ – after [pg/ml]	3.49	3.54	2.40	0.74	4.8	*0.0010*
FT ₄ – before [ng/dl]*	4.48	2.21	1.01	7.84	32.5	*0.0010*
FT ₄ – after [ng/dl]	1.02	1.07	0.44	0.34	1.7

p-value for the Mann-Whitney’s test for a comparison of pairs of measurement results “before” and “after”; SD – standard deviation; p – level of significance.
*Reference ranges:TSH - 0.27-4.2 mIU/l,
FT₄ - 0.93-1.7 ng/dl (1 ng/dl = 1 pmol/l x 12.87),
FT₃ - 2.6-4.4 pg/ml (1 pg/ml = 1 pmol/l x 1.54).

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