Effects of radioiodine administration on serum concentrations of matrix metalloproteinases, adiponectin and thrombospondin-1

Table 2 Descriptive statistics for serum concentrations of matrix metaloproteinases (MMP-2, MMP-9), tissue inhibitors of matrix metalloproteinases (TIMP-1, TIMP-2), adiponectin and thrombospondin-1 (TSP-1) at five (5) consecutive visits – before and after radioiodine therapy, presented with probability values (p-values) of Kruskal-Wallis’ ANOVA for repeated measures design

	VISIT:	n	Mean ± SD	*p-value*
MMP-2 [ng/ml]	before radioiodine	23	393 ± 106	*0.001*
	7 days post	23	373 ± 88
	3 months post	23	423 ± 115
	6 - 8 months post	23	452 ± 124
	15-18 months post	17	774 ± 424
MMP-9 [ng/ml]	before radioiodine	23	631 ± 327	0.68
	7 days post	23	594 ± 353
	3 months post	23	704 ± 364
	6 - 8 months post	23	714 ± 430
	15-18 months post	17	470 ± 106
TIMP-1 [ng/ml]	before radioiodine	23	177 ± 76	*0.00001*
	7 days post	23	186 ± 54
	3 months post	23	215 ± 86
	6 - 8 months post	23	263 ± 128
	15-18 months post	17	296 ± 118
TIMP-2 [ng/ml]	before radioiodine	23	136 ± 44	0.36
	7 days post	23	143 ± 36
	3 months post	23	161 ± 39
	6 -8 months post	23	153 ± 39
	15-18 months post	17	168 ± 41
Adiponectin [ng/ml]	before radioiodine	23	16442 ±9490	*0.001*
	7 days post	23	14430 ± 6216
	3 months post	23	21300 ± 8908
	6 - 8 months post	23	20005 ± 8056
	15-18 months post	17	23518 ± 9840
TSP-1 [ng/ml]	before radioiodine	23	31246 ± 10680	0.72
	7 days post	23	32761 ± 9046
	3 months post	23	32507 ± 10892
	6 - 8 months post	23	33751 ± 8830
	15-18 months post	17	31758 ± 8319

ISSN: 1756-6614