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Table 3 Odds of malignancy using a parsimonius approach with confirmatory bootstrap analysis

From: Predicting malignancy in thyroid nodules: feasibility of a predictive model integrating clinical, biochemical, and ultrasound characteristics

 

Multivariate Analysis (N = 514)

Bootstrap analysis (N = 514)

Variable

Odds Ratio (95%CI)

pa

Odds Ratio (95%CI)

pa

TSH – upper tertile

1.65 (1.28, 2.14)

<0.001

1.65 (1.28, 2.13)

<0.001

Age-group <30 or >60 years

1.20 (0.60, 2.37)

0.61

1.20 (0.57, 2.47)

0.63

Male gender

4.41 (2.06, 9.46)

<0.001

4.41 (1.97. 9.89)

<0.001

Microcalcification

7.33 (3.62, 14.8)

<0.001

7.33 (3.35, 16.1)

<0.001

Echogenicity

1.24 (0.82, 1.86)

0.30

1.24 (0.80, 1.91)

0.34

Irregular margins

3.18 (1.05, 9.63)

0.04

3.18 (0.95, 10.6)

0.06

  1. aCalculated using the Wald Test, Multivariate analysis is analysis adjusted for all variables shown in this table