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Table 3 Baseline characteristics

From: Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) – results from the feasibility randomised controlled trial

 

Total

n =48

Sex

 Female (n,% of females)

34 (71 %)

 Male (n, % of males)

14 (29 %)

Age (years) Median (range)

83.0 (80.0 − 93.0)

Blood pressure (mmHg) Median (IQR)

 Systolic

154.5 (141.0 − 168.5)

 Diastolic

85.0 (77.0 − 92.5)

Physical examination Mean (sd)

 Height (cm)

158.8 (8.8)

 Weight (kg)

68.5 (13.1)

 BMI (kg/m2)

27.1 (4.7)

 Pulse (bpm)

67.9 (9.8)

Chronic conditions n (%)

 Type 2 diabetes mellitus

4 (8.3)

 Hypertension

24 (50)

 Ischaemic heart disease

13 (27.1)

 Cerebrovascular disease

7 (14.6)

 COPD

6 (12.5)

Blood results Median (IQR)

 TSH (mU/L)

1.43 (0.88 − 2.64)

 FT4 (pmol/L)

18.8 (16.7 − 19.7)

 FT3 (pmol/L)

3.8 (3.6 − 4.2)

 Total Cholesterol (mmol/L)

4.9 (4.4 − 6.2)

 HDLc (mmol/L)

1.6 (1.5 − 1.9)

 Triglycerides (mmol/L)

1.3 (1.0 − 1.9)

 Serum CTX (pg/mL)

0.27 (0.17 − 0.37)

 TPO antibodies

  < 35 IU/ml (n, %)

28 (58 %)

  ≥ 35 IU/ml (n, %)

20 (42 %)

  1. IQR interquartile range, sd standard deviation, bpm beats per minute, COPD chronic obstructive pulmonary disease, TSH thyroid stimulating hormone, FT4 free thyroxine, FT3 free triiodothyronine, HDLc high density lipoprotein cholesterol, CTX carboxy-terminal collagen crosslinks, TPO thyroid peroxidase