Case | Age | Sex | Thyroid functiona | TgAb (IU/mL) | TPOAb (IU/mL) | Echo pattern of hypoechoic lesions | US class | BethSysb | Duration of follow-up (months) | Before (mm) | After (mm) | κ/λ deviation ratioc | LT4 supplementation (μg/day) | TSH during follow-up | Outcome |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 53 | F | subclinical hypothyroid (with LT4 50 μg/day) | 4000≦ | 535 | diffuse | 3 | AUSd | 27 | 61 | 47 | 1.21 | 75 | normal | decrease |
2 | 62 | F | hypothyroid | 4000≦ | 600≦ | diffuse | 3.5 | benigne | 30 | 120 | 80 | 1.50 | 112.5 | suppressed | decrease |
3 | 66 | F | euthyroid | 28 | 89 | nodular | 3.5 | AUS | 12 | 25 | 11 | 4.61 | 50 | normal | decrease |
4 | 69 | F | euthyroid | 120.7 | 600≦ | nodular | 3 | AUS | 10 | 37 | disappearance | 3.14 | – | normal | disappearance |
5 | 70 | M | euthyroid | 54 | 118 | nodular | 3 | AUS | 37 | 15 | 12 | 1.84 | – | normal | decrease |
6 | 71 | M | subclinical hypothyroid | 1171 | – | nodular | 3 | malignancy | 6 | 37 | 23 | 3.20 | 50 | normal | decrease |
7 | 72 | F | euthyroid | 906 | – | nodular | 2.5 | Suspicious for malignancy | 3 | 27 | 14 | 2.90 | 50 | normal | decrease |
8 | 74 | F | euthyroid | 512.9 | 151 | nodular | 3 | AUS | 41 | 12 | disappearance | 2.75 | – | normal | disappearance |
9 | 74 | F | euthyroid | 688.8 | 16 | nodular | 3 | Suspicious for malignancy | 1 | 105 | 25 | 1.72 | – | normal | decrease |
10 | 74 | F | euthyroid | 121.8 | – | nodular | 3 | AUS | 7 | 16 | 9 | 2.06 | 75 | suppressed | decrease |
11 | 77 | F | subclinical hypothyroid | 1402 | – | diffuse | 3 | AUS | 25 | 46 | 40 | 1.53 | 50 | normal | decrease |
12 | 83 | F | euthyroid | 89.9 | – | nodular | 3.5 | AUS | 6 | 23 | 19 | 3.21 | – | normal | decrease |
13 | 66 | F | euthyroid | 235.5 | – | nodular | 4 | AUS | 22 | 22 | 22 | 0.86 | 75 | suppressed | no change |
14 | 46 | F | euthyroid | 609.6 | – | nodular | 3 | Suspicious for malignancy | 7 | 22 | 30 | – | – | normal | increase |
15 | 87 | M | euthyroid | 750.4 | ≦16 | nodular | 3 | Suspicious for malignancy | 6 | 19 | 23 | 4.09 | – | normal | increase |
16 | 94 | F | subclinical hypothyroid | 586.3 | 26.5 | diffuse | 3 | Suspicious for malignancy | 11 | 65 | 160 | 1.81 | 62.5 | normal | increase |