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Table 2 Laboratory findings at baseline (t0) and reassessment (t1)

From: The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?

Parameter

Group

t0

t1

t1- t0 (mean, 95% CI)

    

Difference

% Difference

TSH

Treated (N = 57)

1.82 ± 0.14

1.95 ± 0.12

0.13( -1.23; 1.5)

16.62 (-75.45; 108.69)

Controls (N = 31)

2.13 ± 0.15

2.18 ± 0.13

-0.05 (-0.78; 0.68)

-2.22(-35.5; 31.07)

P value (T vs C)

0.091

0.290

  

FT4

Treated

1.13 ± 0.02

1.10 ± 0.02

-0.03 (-0.24; 0.17)

-2.64 (-21.05; 15.78)

Controls

1.17 ± 0.02

1.19 ± 0.02

0.02(-0.14; 0.18)

1.55(-11.77; 14.86)

P value (T vs C)

0.216

0.024

  
  1. TSH Thyroid-stimulating hormone concentrations in mIU/L, FT4 Free thyroxin levels in ng/dL, T-group Treated-group, C-group Control-group, t0 Basal measurement, t1 Second measurement, N Number of participants, % Percentage of difference
  2. P, Mann–Whitney U test; Data presented as means ± SEM