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Table 3 Pertinent data of studied subjects’ characteristics stratified according to biotin dose

From: The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?

Biotin dose

TSH

Biotin

TSH

Withdrawal

P

FT4

Biotin

FT4

Withdrawal

P

Total (N = 57)

1.82 ± 0.14

1.95 ± 0.12

0.029*

1.13 ± 0.02

1.10 ± 0.02

0.024

 ≤ 100 μg/day (N = 40)

2.13 ± 0.28

2.10 ± 0.19

0.253

1.13 ± 0.03

1.11 ± 0.02

0.160

 > 100–300 μg/day(N = 17)

1.62 ± 0.17

1.89 ± 0.20

 < 0.05

1.13 ± 0.04

1.08 ± 0.04

0.07

  1. TSH Thyroid-stimulating hormone concentrations in mIU/L, FT4 Free thyroxin levels in ng/dL, N Number of patients, P, Wilcoxon nonparametric test
  2. * paired t-test; Data presented as means ± SEM
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Thyroid Research

ISSN: 1756-6614