Table 1 Summary of cases with asymmetrical lacrimal gland swelling
Case | Age | Gender | Medical History | Presentation | Thyroid status | Clinical Activity Score | MRI Findings | Lacrimal Gland Biopsy | Histopathology |
|---|---|---|---|---|---|---|---|---|---|
1 | 62 | M | Asthma | Left upper lid retraction 4mm left proptosis No treatment prior to biopsy | Hyperthyroid | 2/7 | Asymmetrical left lacrimal gland enlargement | Left lacrimal gland biopsy 27 days after presentation | Preservation of the architecture within the lacrimal gland. There are occasional focal areas of lymphocytes and occasional plasma cells within the lobules |
2 | 42 | F | HIV | 5mm left proptosis Limitation of abduction OS Limitation of elevation OS No treatment prior to biopsy | Hyperthyroid | 1/7 | Asymmetrical eft lacrimal gland enlargement | Left lacrimal gland biopsy 13 days after presentation | Extensive infiltration of small mature lymphocytes, surround and infiltrate lacrimal ducts. Occasional plasma cells. Expanded B cell population, no evidence of monoclonality. Extensive positivity for IgG but not IgG4 |
3 | 63 | F | Morbid obesity Type 2 Diabetes Mellitus Hypertension Polycystic Ovarian Syndrome | Right upper lid retraction Oedema of right upper lid Right lid lag Right upper lid subconjunctival triamcinolone injection at time of presentation | Hyperthyroid | 1/7 | Asymmetrical right lacrimal gland enlargement | Right lacrimal gland biopsy 76 days after presentation | Small lymphoid population without evidence of fibrosis |
4 | 68 | F | Nil | Left upper lid retraction Left lid lag No treatment prior to biopsy | Hyperthyroid | 2/7 | Asymmetrical left lacrimal gland enlargement | Left lacrimal gland biopsy 20 days after presentation | Small patchy and predominantly lymphoid infiltrates. Presence of fibrosis. Mixed B cell population. CD20 + B Cells and CD3 + ve T Cells |