Fig. 1

Screening for differentially expressed genes (DEGs) in THCA and functional enrichment analysis of these DEGs. A Volcano map for DEG screening with volcanoes plotted using fold change and corrected p-values. Red dots in the schematic indicate genes that are significantly differentially up-regulated, blue dots indicate genes that are significantly differentially down-regulated, and grey dots indicate genes that are not significantly regulated. B Heat map for clustering analysis of DEGs with different colors representing the expression trends in different tissues. Due to the large number of DEGs, only 50 up-regulated and 50 down-regulated genes with the greatest differential change are shown here. C KEGG analysis of highly expressed DEGs. D GO analysis of highly expressed DEGs. E KEGG analysis of DEGs with low expression. F GO analysis of DEGs with low expression. The different colors represent the significance of the differential enrichment results with the larger values representing smaller FDR values. The size of the circles represents the number of enriched genes with the larger circles representing the larger number of genes