From: Radiofrequency ablation for thyroid nodules in Ecuador: a cross-sectional study
Radiofrequency ablation benign nodule (n = 36) | Radiofrequency Microcarcinoma (n = 8) | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Baseline | 1 m | 3 m | 6 m | 12 m | p-value | Baseline | 1 m | 3 m | 6 m | 12 m | |
Longest tumor diameter (mm) | 36 (21–43) n = 36 | 31 (12–35) n = 22 p = < 0.001 | 33 (11-38.5) n = 7 p = 0.0042 | 20 (11–21) n = 9 p = 0.0025 | 10 (7–17) n = 8 p = 0.0018 | < 0.05 | 8.5 (7–10) n = 8 | 9 (7.5–10) n = 4 p = 0.2319 | 8 (5.5–8.5) n = 3 p = 0.7157 | 3 (1.5-5) n = 3 p = 0.09418 | - |
Tumor volume (ml) | 10.3 (1.86–18.97) n = 36 | 6.9 (0.48–10.15) n = 21 p = 0.00021 | 5.72 (0.77–7.25) n = 7 p = 0.045 | 0.98 (0.25–3.64) n = 11 p = 0.0077 | 0.11 (0.07–11.26) n = 8 p = 0.0264 | < 0.05 | 0.25 (0.19–0.48) n = 8 | 0.19 (0.12–0.31) n = 4 p = 0.1168 | 0.10 (0.05–0.15) n = 3 p = 0.1306 | 0.01 (0.005–0.04) n = 3 p = 0.3642 | - |
Volume reduction ratio (%) | - | 47.25 (36.38–64.17) n = 22 | 72.20 (62-73.20) n = 5 p = 0.019 | 74 (49–82) n = 9 p = 0.032 | 96.20 (85.4–97.80) n = 7 p = 0.076 | < 0.05 | - | 42 (64-81.35) n = 3 | 52.5 (29.59–75.42) n = 2 | 94.85 (92.28–97.42) n = 2 | - |
TSH | 1.71 (1.4–2.45) n = 32 | 1.37 (0.81–2.12) n = 8 p = 0.97 | 2.6 (1.69–3.46) n = 6 p = 0.578 | 1.97 (1.31–2.52) n = 6 p = 0.33 | 2.32 (1.88–2.66) n = 6 p = 0.24 | > 0.05 | 1.43 (041-2.72) n = 6 | 2.27 (2.14–2.75) n = 4 p = 0.1614 | 2.14 (2.09–2.17) n = 3 p = 0.092 | 1.30 (1.3) n = 2 | - |
Cosmetic score (1–4) | 2.00 (1–2) n = 36 | 1.00 (1–1) n = 16 | 1.00 (1–1) n = 10 | 1.00 (1–1) n = 9 | 1.00 (1–1) n = 4 | < 0.001 | 1 (1–2) n = 8 | 1 (1) n = 6 p = 0.3632 | 1 (1) n = 3 p = 0.4226 | 1 (1) n = 2 p = NA | 1 (1) n = 2 p = NA |
Symptom score (0–10) | 2.5 (1.75–4.25) n = 36 | 1.00 (1–1) n = 16 | 1.00 (1–1) n = 12 | 1.00 (1–1) n = 7 | 0 (0–0) n = 4 | < 0.001 | 0 (0–1) n = 8 | 0 (0) n = 5 p = 0.3739 | 0 (0) n = 3 p = NA | 0 (0) n = 2 p = NA | 0 (0) n = 2 p = NA |