Table 1 Clinicopathological and ultrasound characteristics of patients according to central lymph node metastasis in the training cohort
Characteristic | CLNM group (N = 110) | Non-CLNM group (N = 217) | P value |
|---|---|---|---|
Age, years | 0.006 | ||
< 45 | 67 (60.9%) | 97 (44.7%) | |
≥ 45 | 43 (39.1%) | 120 (55.3%) | |
Sex | 0.061 | ||
Female | 81 (73.6%) | 179 (82.5%) | |
Male | 29 (26.4%) | 38 (17.5%) | |
Tumor size, cm | < 0.001 | ||
< 0.7 | 45 (40.9%) | 137 (63.1%) | |
≥ 0.7 | 65 (59.1%) | 80 (36.9%) | |
Multifocality | 0.097 | ||
No | 67 (60.9%) | 152 (70.0%) | |
Yes | 43 (39.1%) | 65 (30.0%) | |
Laterality | 0.100 | ||
Unilateral | 84 (76.4%) | 182 (83.9%) | |
Bilateral | 26 (23.6%) | 35 (16.1%) | |
Margin | 0.365 | ||
Smooth | 34 (30.9%) | 78 (35.9%) | |
Irregular | 76 (69.1%) | 139 (64.1%) | |
Calcification | 0.003 | ||
Absent | 48 (43.6%) | 132 (60.8%) | |
Presence | 62 (56.4%) | 85 (39.2%) | |
Capsule invasion | 0.014 | ||
Absent | 96 (87.3%) | 206 (94.9%) | |
Present | 14 (12.7%) | 11 (5.1%) | |
Hypoechoic | 0.530 | ||
No | 12 (10.9%) | 19 (8.8%) | |
Yes | 98 (89.1%) | 198 (91.2%) | |
BRAF V600E mutation | 0.009 | ||
Wild-type | 35 (31.8%) | 102 (47.0%) | |
Mutant | 75 (68.2%) | 115 (53.0%) |