Fig. 4From: Evaluating the progression to abnormal thyrotropin in euthyroid preconception women: a population-based studyDose–response association between baseline thyrotropin level or thyrotropin MOM and risk of developing abnormal thyrotropin. Cox proportional hazard regression model was adjusted for age, body mass index, parity, education level, alcohol consumption, passive smoking, diabetes, hypertension, and environmental iodine nutrition status. Reference values were thyrotropin 1.75 mIU/L (A) and thyrotropin MOM 1.00 (B). Black curves indicate HR estimate; shaded areas indicate 95% confidence intervals. Abbreviations: TSH, thyrotropin; MOM, multiples of the median; HR, hazard ratios. Note: The specific number of knots of each model: A: 4; B:7Back to article page