Multiple adverse thyroid and metabolic health signs in the population from the area heavily polluted by organochlorine cocktail (PCB, DDE, HCB, dioxin)

Table 1 Adverse health signs in quintiles of stratified PCB level in a total of 2046 examined males and females

	Quintiles of serum PCB level
	1 (n = 409)	2 (n = 409)	3 (n = 410)	4 (n = 410)	5 (n = 408)
Adverse signs ¹⁾	Upper PCBs level for each quintile(ng/g lipid)					Chi-square	p
	627	906	1341	2343	101,413
	Number of adverse health cases per quintile
1. Increased thyroid volume	79	79	84	122	124	29.30	0.0000
2. Positive TPOab	83	98	88	126	116	17.56	0.0015
3. Positive TRab	82	93	97	84	69	6.88	0.1423
4. Increased free T4	70	84	114	104	128	28.58	0.0000
5. Increased total T3	100	105	116	139	132	13.44	0.0093
6. Decreased TSH	4	5	12	7	20	18.56	0.0010
7. Increased TSH	55	65	48	56	45	5.17	0.2701
8. Increased thyroglobulin	38	44	27	38	42	5.11	0.2759
9. Increased fasting glucose	171	190	235	272	295	110.55	0.0000
10. Increased fasting insulin	88	86	94	105	122	11.89	0.0182
11. Increased cholesterol	89	119	127	142	134	8.76	0.0673
12. Increased triglycerides	89	119	127	142	134	19.36	0.0007
13. Increased BMI	131	157	149	146	161	5.84	0.2118