Thyroid Research

Table 2 Uptake of iodothyronines by TH transporters expressed at the blood-brain barrier. The levels of TH transport are indicated as follows: +++ high uptake rate, ++ modest uptake rate, and + low uptake rate; n.d., not determined.

From: Primary and secondary thyroid hormone transporters

Protein	Iodothyronines				Species	References
	3,3`-T ₂	T ₃	rT ₃	T ₄
MCT8	+/+	+++/+++	+/++	++/++	human/rat	[14, 86]
OATP1C1	n.d.	+	+++	+++	human, rat, mouse	[37–39]
LAT1	+++	++	++	+	human	[43]
LAT2	+++	++	++	+	mouse	[43]

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ISSN: 1756-6614

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