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Table 2 Results of flow cytometry of fine needle biopsy specimen from the left thyroid lobe lesion

From: Case report: rare case of infiltration of small lymphocytic B-cell lymphoma in the thyroid gland of female patient with B-cell chronic lymphocytic leukemia (CLL-B/SLL-B)

Type of cell Fraction [%]
Mature lymphocytes CD45++ (CD3 83.3%, CD4 69%, CD8 7.9%, CD5 90%) 2%
Neutrophils (16+/10-+/11c+/11b+/CD33-) 36%
Cellular conglomerates, debris, necrotic material (?) 25%
Atypical cells (larger, with large granules; some of them undergo apoptosis despite retained antigen expression) 37%
Immunophenotype of atypical cells CD20 – 100%, CD23 – 98.6%, CD5 – 99.4%, CD79b – 32.5%, CD22 – 41.8%, CD8 – 81.2%, CD56 – 91.4%, CD16 – 27.3%, CD71 – 93.3%, CD19 – 60.7%, CD13 – 35.2%, FMC-7 31.3%. Other antigens: CD3, CD4, CD38, CD11b, CD11c, CD10, kappa, and lambda were negative.