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Table 1 Distribution of US characteristics in malignant and benign thyroid lesions; p values indicating a statistical significance are marked by bold

From: Proposed algorithm for management of patients with thyroid nodules/focal lesions, based on ultrasound (US) and fine-needle aspiration biopsy (FNAB); our own experience

Parameter

No. of cases (%)

Malignant lesions

Benign lesions

p value

No. of cases (%)

No. of cases (%)

Vascularity

    

Intranodular and increased or completely absent

150 (75.0)

96 (64.0)

54 (46.0)

<0.0001

Peripheral, subcapsular

50 (25.0)

4 (8.0)

46 (92.0)

 

Microcalcifications

    

Positive

128 (64.0)

93 (72.7)

35 (27.3)

<0.0001

Negative

72 (36.0)

7 (9.7)

65 (90.2)

 

Orientation

    

Taller-than-wide

88 (44.0)

86 (97.7)

2 (2.3)

<0.0001

Wider-than-tall or of other shape

112 (56.0)

14 (12.5)

98 (87.5)

 

Composition

    

Solid

173 (86.5)

94 (54.3)

79 (65.7)

0.0032

Mixed

27 (23.5)

6 (22.2)

21 (77.8)

 

Echogenicity

    

Hypoechogenic

106 (53.0)

84 (79.2)

22 (20.1)

<0.0001

Isoechogenic

94 (47.0)

16 (17.0)

78 (83.0)

 

Margins

    

Irregular

107 (53.5)

77 (71.9)

30 (28.1)

<0.0001

Well circumscribed

93 (46.5)

23 (24.7)

70 (75.3)

 

Peripheral Halo

    

Absent or irregular, thick

111 (55.0)

76 (68.0)

35 (32.0)

<0.0001

Present, thin and regular

89 (45.0)

24 (27.0)

65 (73.0)

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