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Table 2 Values of sensitivity, specificity, PPV and NPV of the analyzed US characteristics (parameters)

From: Proposed algorithm for management of patients with thyroid nodules/focal lesions, based on ultrasound (US) and fine-needle aspiration biopsy (FNAB); our own experience

Parameter

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Vascularity

96 (90–99)

46 (36–56)

64 (56–72)

92 (80–98)

Microcalcifications

93 (86–97)

65 (54–74)

73 (64–80)

90 (80–96)

Orientation

86 (77–92)

98 (93–99)

97 (92–99)

87 (80–93)

Composition

94 (87–97)

21 (13–30)

54 (46–61)

77 (57–91)

Echogenicity

84 (75–90)

78 (68–85)

79 (70–86)

82 (73–89)

Margins

77 (67–84)

70 (60–78)

72 (62–80)

75 (65–83)

Peripheral Halo

76 (66–84)

65 (56–74)

68 (59–77)

73 (62–82)

  1. The 95% confidence intervals are given in the brackets.