Table 5 Summarized previous reports concerning relationship between thyroid diseases and breast cancer or benign breast tumors

n

150

100

-

66

49

-

36

100

-

100

75

-

26

22

-

Age-yr means ± SD (min-max)

63 (38–80)

age-matched

-

63.5 ± 11.8

68.4 ± 12.8

ns

52.8 ± 10.2

age-matched

-

63 (38–80)

-

-

(30–85)

age-matched

-

TSH

3.12 ± 1.40

1.46 ± 0.82

ns

1.77 (0.15-47.9)

1.52 (0.45-14.56)

ns

1.9 ± 0.7

1.8 ± 1.4

ns

4.12 ± 1.40

1.39 ± 0.79

0.030

1.36 ± 0.63

2.41 ± 0.35

<0.05

units

μIU/ml

mIU/dl

μIU/ml

μIU/ml

μU/ml

FT ₄

2.64 ± 0.91

1.42 ± 0.31

ns

15.70 (7.38-22.63)

15.19 (10.5-21.5)

ns

9.76 ± 2.73

9.9 ± 2.4

ns

2.93 ± 0.57

1.39 ± 0.21

0.030

1.40 ± 1.64

1.10 ± 0.83

<0.05

units

ng/dl

pmol/dl

pg/ml

ng/dl

ng/dl

FT ₃

8.47 ± 0.75

4.48 ± 0.75

ns

-

3.58 ± 0.7

3.2 ± 0.6

ns

7.25 ± 0. 75

3.42 ± 0.91

0.030

3.56 ± 3.14

2.87 ± 3.12

<0.001

units

pmol/l

pg/ml

pmol/l

pmol/ml

TgAb

140.92 ± 21.52

27.75 ± 7.60

ns

35.80 (26.1-6000.0)

27.70 (18.5-298.0)

<0.001

12/36

12/100

p < 0.01

-

-

units

IU/ml

kIU/dl

Patients’ ratio with positive TgAb

TPOAb

105.82 ± 21.46

23.08 ± 4.16

0.030

6.10 (6.1-871.0)

6.10 (6.1-1621.6)

ns

12/36

8/100

p < 0.01

104.57 ± 19.39-

24.81 ± 5.16

0.030

-

units

IU/ml

kIU/dl

Patients’ ratio with positive TPOAb

IU/ml

Diagnosis

BC

C

p

BC

C

p

-

Graves’ disease

-

0/66

0/49

-

AITD

57/150

17/100

0.001

16/66

8/49

-