Table 1 Technical problems in serum Ct measurement
1. Serum not appropriately stored (i.e -20°C) may give false negative results |
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2. Very high values can give false negative results (Hook effect) |
3. Some drugs, such as omeprazole, can stimulate Ct and produce false positive results* |
4. Heterophylic antibodies may give false positive results* |
5. Normal range should be calculated in each laboratory |
6. Analytical and functional sensitivity of the assay should be verified in each laboratory |