Table 1 Evaluation of somatostatin analogues in advanced medullary thyroid cancer.
From: Clinical comments related to medullary thyroid cancer diagnosis and management
Reference | Study | Treatment / Duration | No. of patients | Outcome |
|---|---|---|---|---|
Vainas I et al. 2004 | OS | Octreotide-(LAR)/ 21 months | 22 | No improvement of the natural course |
Diez IJ, Iglesias P 2002 | OS | Octreotide / Lanreotide / 12 weeks | 5 | No effect |
Frank-Raue K et al. 1993 | OS | Octreotide | 7 | No effect No beneficial effect on diarrhea |
Mahler C et al. 1990 | CR | Octreotide / 17 months | 1 2 | Tachyphylaxis |
Modigliani E et al. 1989 | OS | Octreotide / 37 days | 18 | Improvement of diarrhea in 2/9 |