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Table 1 The clinical, biochemical and hormonal results in patients with Hashimoto’s thyroiditis and healthy control

From: Serum macrophage migration inhibitory factor levels in Hashimoto’s thyroiditis; a case control study

Variable

Group 1

Group 2

Group 3

Group 4

p

(n = 52)

(n = 31)

(n = 10)

(n = 53)

Age (years)

30.7 ± 9.9

30.1 ± 10

38 ± 17.6

29.3 ± 8.5

0.702*

Gender (F/M)

47/5

28/3

8/2

83%

0.572**

FT3 (pg/ml)

3.1 ± 0.2

3.1 ± 0.3

3.1 ± 0.4

3.2 ± 0.3

0.252*

FT4 (ng/dl)

1.0 ± 0.1

1.0 ± 0.1

0.8 ± 0.1

1.09 ± 0.12

<0.001*

TSH (μIU/ml)

2.3 ± 1.1

6.7 ± 1.6

23.6 ± 27.2

1.8 ± 0.9

<0.001*

TGAb (uIU/ml)

225.5 ± 281.4

239.5 ± 319.4

229.8 ± 248.1

1.7 ± 1.5

<0.001*

TPOAb (uIU/ml)

221.8 ± 361.4

386.7 ± 376.5

629.8 ± 464.1

0.7 ± 3

<0.001*

MIF(pg/ml)

3955.2 ± 3013.6

4599.8 ± 2717.9

6300.9 ± 2504.3

4971.2 ± 3054.4

0.044*

  1. Values are expressed as means ± SD.
  2. * Kruskal Wallis ** Chi square test.
  3. Group 1: euthyroid Hashimoto’s thyroiditis, group 2: subclinical hypothyroidism, group 3: overt hypothyroidism, group 4: control group. FT3; free T3, FT4; free T4, TSH; thyroid stimulating hormone, TGAb; anti-thyroglobulin autoantibody, TPOAb; anti-thyroid peroxidase autoantibody, MIF; Macrophage migration inhibitory factor.
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Thyroid Research

ISSN: 1756-6614