Fig. 1

Prevalence of tumors in animals versus iodine intake. a Prevalence of animals with thyroid adenoma and thyroid carcinoma at week 26 after a single 2.8 mg/kg DHPN dose at week 2 and under one of seven long-term deficient, sufficient or excessive iodine diets (deficient intake: 0.25, 0.4, 0.55, 0.84 μg/day; normal intake: 2.6 μg/day; excessive intake: 760, 3000 μg/day) [33]. b Prevalence of animals with thyroid adenoma and thyroid carcinoma at week 110 after a single exposure to 4-Gy external radiation at week 6 and under one of three long-term deficient, sufficient or excessive iodine diets (deficient intake: 0.42 μg/100 g body weight/day; normal intake: 7 μg/100 g body weight/day; excessive intake: 72 μg/100 g body weight/day) [36]. Shaded area: range of normal iodine intake.