|
Country (reference)
|
Year
|
No. autopsy cases
|
% with occult thyroid cancer
|
|---|
|
Probable deficient iodine intake (UIC < 100 μg/L) (n = 11)
|
|
Italy [151]
|
1982
|
111
|
3.6
|
|
Chile [152]
|
1984
|
274
|
2.9
|
|
Poland [108]
|
1975
|
110
|
6.6
|
|
Portugal [153]
|
1979
|
600
|
1.0
|
|
Israel [154]
|
1981
|
260
|
4.2
|
|
Germany [155]
|
1987
|
1020
|
6.1
|
|
Spain [156]
|
1993
|
100
|
22.0
|
|
Belarus [157]
|
1993
|
215
|
8.8
|
|
Ukraine [158]
|
1996
|
162
|
10.8
|
|
Guatemala [159]
|
2005
|
150
|
2.0
|
|
Hungary [109]
|
2005
|
222
|
5.0
|
|
Mean
| | |
6.6
|
|
Weighted mean
| | |
5.3
|
|
Probable sufficient iodine intake (UIC = 100–299 μg/L) (n = 10)
|
|
Canada [108]
|
1975
|
100
|
6.0
|
|
Sweden [160]
|
1981
|
500
|
6.4
|
|
USA [161]
|
1988
|
138
|
2.9
|
|
Brazil [162]
|
1989
|
300
|
1.0
|
|
Argentina [163]
|
1989
|
100
|
11.0
|
|
Iceland [164]
|
1992
|
199
|
6.0
|
|
Singapore [165]
|
1994
|
444
|
9.0
|
|
Austria [110]
|
2001
|
118
|
8.6
|
|
Greece [166]
|
2002
|
160
|
5.6
|
|
Turkey [167]
|
2011
|
108
|
3.7
|
|
Mean
| | |
6.0
|
|
Weighted mean
| | |
6.0
|
|
Probable excessive iodine intake (UIC ≥ 300 μg/L) (n = 10)
|
|
USA [168]
|
1952
|
429
|
0.9
|
|
USA [169]
|
1955
|
1000
|
2.8
|
|
USA [170]
|
1955
|
221
|
1.4
|
|
USA [171]
|
1964
|
100
|
4.0
|
|
USA [172]
|
1966
|
300
|
2.7
|
|
USA [173]
|
1969
|
220
|
0.5
|
|
USA [174]
|
1974
|
157
|
5.7
|
|
Columbia [108]
|
1975
|
607
|
5.6
|
|
Hungary [109]
|
2005
|
221
|
4.5
|
|
Brazil [175]
|
2006
|
166
|
7.8
|
|
Mean
| | |
3.6
|
|
Weighted mean
| | |
3.3
|
|
Studies of Japanese populations in areas of excessive iodine intake (n = 5)
|
|
USA, Japanese [176]
|
1971
|
100
|
24.0
|
|
Japan [174]
|
1974
|
1096
|
17.9
|
|
USA, Japanese [108]
|
1975
|
248
|
24.2
|
|
Japan [108]
|
1975
|
1167
|
28.4
|
|
Japan [111]
|
1990
|
408
|
15.7
|
|
Mean
| | |
22.0
|
|
Weighted mean
| | |
22.4
|
-
aWeighted means of iodine intake categories compared by using the Chi-squared test of independence: <100 μg/L vs. 100–299 μg/L (p = 0.244); ≥300 μg/L vs. <100 μg/L or 100–299 μg/L (both, p < 0.001)
