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Table 2 Associations between thyroid hormones and patient demographics, baseline function, stroke severity, medical history, and medication usage

From: Thyroid hormones and functional outcomes after ischemic stroke

 

TSH

fT3

fT4

Demographic associations

   

  TSH

NS

NS

R = −0.246*

  Sex

NS

NS

NS

  Age

NS

R = −.332***

NS

Pre-stroke associations

   

  Baseline mRS

NS

R = −0.393***

NS

  Baseline mBI

NS

R = 0.295***

NS

Admission associations

   

  Admission NIH

NS

R = −0.191*

NS

  Hospital mRS

R = −0.206

NS

R = 0.176*

  Admission mBI

NS

NS

NS

Other associations

   

  Past medical history

   

   Hypertension

NS

NS

NS

   Heart disease

NS

NS

NS

   Prior stroke

NS

NS

NS

   Diabetes

NS

NS

NS

   Depression

NS

NS

NS

   Alcohol use

NS

NS

NS

  Medications

   

   Anti-platelets

NS

NS

NS

   Anticoagulants

NS

NS

NS

   Anti-hypertensives

NS

NS

NS

   Anti-cholesterol

NS

NS

NS

  1. Associations between thyroid hormones and demographics upon hospital admission. Patients with low levels of fT3 had increased disability and poorer pre-stroke function. NIH score on admission was inversely associated with fT3. Hospital mRS was inversely associated with TSH and directly associated with fT4. None of the thyroid hormones were associated with past medical history of hypertension, heart disease, prior stroke, diabetes, depression, alcohol use, or with the usage of anti-platelets, anti-coagulants, anti-hypertensives, or anti-cholesterol medications
  2. *p < 0.05; **p < 0.01; ***p < 0.001