Fig. 4

a Well-differentiated follicular carcinoma: TPO expression appears positive in normal thyroid cells and negative in tumor cells (TPO x20); b Papillary carcinoma: positive TPO expression in the apical portion of epithelial cells and negative in Psammoma bodies (TPO x40); c Undifferentiated carcinoma: negative TPO expression (TPO x40); d Medullary carcinoma: expression of TPO in cytoplasmic vesicles (TPO x20)