Skip to main content

Table 3 Diagnostic performance of TSHR mRNA, serum Tg, and 131I uptake in identifying structural persistent disease

From: Circulating thyrotropin receptor messenger ribonucleic acid is not an effective marker in the follow-up of differentiated thyroid carcinoma

 

Diagnostic Performance (%)

TSHR mRNAa

Serum Tgb

131I whole body scan

Total

TgAb-ve

TgAb + ve

Total

TgAb-ve

TgAb + ve

Total

TgAb-ve

TgAb + ve

Sensitivity

62.3

53.8

88.2

79.7

90.4

47.1

46.4

42.3

58.8

Specificity

42.9

42.9

42.9

81.6

81.6

81.6

87.8

87.8

87.8

PPVc

60.6

50.0

34.9

85.9

83.9

47.1

84.2

78.6

62.5

NPVd

44.7

46.7

91.3

74.1

88.9

81.6

53.8

58.9

86.0

Accuracy

54.2

48.5

54.5

80.5

86.1

72.7

63.6

64.4

80.3

  1. aUsing a cutoff of at least 2.00 pg equivalents/μg total RNA on thyroid hormone therapy
  2. bUsing a cutoff of at least 0.3 ng/mL on thyroid hormone therapy
  3. cPPV, Positive predictive value
  4. dNPV, Negative predictive value