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Fig. 2 | Thyroid Research

Fig. 2

From: Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73

Fig. 2

a Evolution of viable TT cell number in control wells and in wells treated by NSAID/GTN combination: 25 μM celecoxib plus 100 μM GTN (cele + GTN), or 100 μM indomethacin plus 100 μM GTN (indo + GTN), or 150 μM NCX 530 (NO-indo), during 8 days. b Evolution of viable TT cell populations after cessation of treatments with NSAID/GTN bi-therapies or NCX 530 (25 μM celecoxib, 100 μM indomethacin, 100 μM GTN or 150 μM NCX 530). Representative graphs of two independent experiments performed in triplicates. Adherent cells were dissociated with trypsin-EDTA and count with a hemocytometer. *** = P < 0.001 versus control for each treatment (Fisher tests)

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Thyroid Research

ISSN: 1756-6614