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Figure 3 | Thyroid Research

Figure 3

From: Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73

Figure 3

Expression of various proteins in TT cells after 3 days of exposition to 25 μM celecoxib (cele), 100 μM indomethacin (indo), 100 μM GTN or NSAID/GTN combinations. a PCNA protein. For each category, n = 6 to 3. b PARP heavy chain. For each category, n = 4 to 3. c Tumor suppressor p53. For each category, n = 4 to 2. d TAp73α. For each category, n = 7 to 4. Graphs obtained from associated results of two experiments on TT cells. Proteins from TT cell lysates were separated by SDS-PAGE using 10 % acrylamide gel and transferred onto nitro cellulose membranes. Immunoblots were probed with specific antibodies and a α-tubulin (internal control) antibody. * = P < 0.05, *** = P < 0.001 versus control (Fisher tests)

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