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Fig. 4 | Thyroid Research

Fig. 4

From: Apoptosis induction by combination of drugs or a conjugated molecule associating non-steroidal anti-inflammatory and nitric oxide donor effects in medullary thyroid cancer models: implication of the tumor suppressor p73

Fig. 4

a Effect of p73 siRNA pre-treatment on TAp73 and PARP expressions in TT cells receiving 25 μM celecoxib plus 100 μM GTN (combi) during 2 days and 8 h. b Effect of p73 siRNA pre-treatment on TAp73 expression in the same TT cells. c Effect of p73 siRNA pre-treatment on full length PARP expression in these cells. Graphs obtained from associated results of two experiments on TT cells. For each category, n = 6 to 4. Proteins from TT cell lysates were separated by SDS-PAGE using 10 % acrylamide gel and transferred onto nitro cellulose membranes. Immunoblots were probed with specific antibody and a α-tubulin (internal control) antibody. * = P < 0.05, ** = P < 0.01 (Fisher tests)

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Thyroid Research

ISSN: 1756-6614