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Table 6 High dose L-T4 test in Patient III (1000 μg twice within 48 h)

From: A single bolus of high dose levothyroxine (L-T4) as a test in cases of suspected poor compliance to L-T4 therapy

Date TSH (μIU/ml) Reference range (μIU/ml) FT4 (ng/dl) Reference range (ng/dl) FT3 (pg/ml) Reference range (pg/ml)
Day 0a (8.00 AM) 18.64 0.27–4.2 0.36 0.93–1.7 0.86 2.6–4.4
Day 0 (6.00 PM) 20.37 0.27–4.2 1.18 0.93–1.7 1.56 2.6–4.4
Day 1 17.43 0.27–4.2 1.08 0.93–1.7 1.72 2.6–4.4
Day 2a (8.00 AM) 15.69 0.27–4.2 2.08 0.93–1.7 1.98 2.6–4.4
Day 3 11.54 0.27–4.2 1.71 0.93–1.7 2.34 2.6–4.4
Day 4 12.60 0.27–4.2 1.58 0.93–1.7 2.31 2.6–4.4
Day 5 8.50 0.27–4.2 1.46 0.93–1.7 2.21 2.6–4.4
  1. a received 1000 μg of L-T4 (Euthyrox N®) as a single fasting dose