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Table 6 High dose L-T4 test in Patient III (1000 μg twice within 48 h)

From: A single bolus of high dose levothyroxine (L-T4) as a test in cases of suspected poor compliance to L-T4 therapy

Date

TSH (μIU/ml)

Reference range (μIU/ml)

FT4 (ng/dl)

Reference range (ng/dl)

FT3 (pg/ml)

Reference range (pg/ml)

Day 0a (8.00 AM)

18.64

0.27–4.2

0.36

0.93–1.7

0.86

2.6–4.4

Day 0 (6.00 PM)

20.37

0.27–4.2

1.18

0.93–1.7

1.56

2.6–4.4

Day 1

17.43

0.27–4.2

1.08

0.93–1.7

1.72

2.6–4.4

Day 2a (8.00 AM)

15.69

0.27–4.2

2.08

0.93–1.7

1.98

2.6–4.4

Day 3

11.54

0.27–4.2

1.71

0.93–1.7

2.34

2.6–4.4

Day 4

12.60

0.27–4.2

1.58

0.93–1.7

2.31

2.6–4.4

Day 5

8.50

0.27–4.2

1.46

0.93–1.7

2.21

2.6–4.4

  1. a received 1000 μg of L-T4 (Euthyrox N®) as a single fasting dose