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Table 2 Odds Of Malignancy In Univariate And Multivariate Analyses

From: Predicting malignancy in thyroid nodules: feasibility of a predictive model integrating clinical, biochemical, and ultrasound characteristics

 

Univariate analysis (n = 536)

Multivariate analysis (n = 422)

Variable

OR (95%CI)

pa

OR (95%CI)

pa

TSH – upper tertile

1.52 (1.19, 1.92)

0.001

1.53 (1.10, 2.12)

0.01

FT4 - upper tertile

0.82 (0.66, 1.02)

0.08

0.84 (0.61, 1.15)

0.28

Age-group (<30 or > 60 yrs)

1.16 (0.64, 2.09)

0.62

1.17 (0.51, 2.71)

0.71

Male gender

3.83 (2.04, 7.17)

<0.001

3.45 (1.33, 8.92)

0.01

Smoker

0.93 (0.64, 1.38)

0.75

1.02 (0.65, 1.60)

0.93

Size group

0.79 (0.55, 1.15)

0.23

0.78 (0.45, 1.37)

0.40

Microcalcification

7.55 (4.07, 14.0)

<0.001

6.32 (2.82, 14.1)

<0.001

Nodularity

1.09 (0.59, 2.01)

0.78

0.79 (0.36, 1.76)

0.57

Hypo-echogenicity

1.52 (1.09, 2.10)

0.01

1.17 (0.73, 1.89)

0.51

Irregular margins

4.49 (1.76, 11.4)

0.002

5.45 (1.61, 18.6)

0.006

Solid composition

1.24 (0.82, 1.87)

0.31

1.05 (0.62, 1.77)

0.84

  1. aCalculated using the Wald Test; Multivariate analysis is analysis adjusted for all variables shown in this table