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Table 4 Dose titration strategy and compliance with study medications

From: Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) – results from the feasibility randomised controlled trial

Dose titration strategy:
Participants who remained in the study until their final study assessment (i.e. excluding withdrawals), n = 40
Usual TSH range (0.4–4.0 mU/L)
n = 21
Higher TSH range (4. 1–8.0 mU/L)
n = 19
Percent achieving target TSH range at week 12 (visit 2) 18/21 (85.7 %) 6/19 (31.6 %)
Percent achieving target TSH range at week 24 (visit 3) 18/21 (85.7 %) 10/19 (52.6 %)
Percent compliant at week 12 (visit 2) 21/21 (100 %) 18/19 (94.7 %)
Percent compliant at week 24 (visit 3) 21/21 (100 %) 18/19 (94.7 %)