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Table 4 Dose titration strategy and compliance with study medications

From: Study of Optimal Replacement of Thyroxine in the Elderly (SORTED) – results from the feasibility randomised controlled trial

Dose titration strategy:

Participants who remained in the study until their final study assessment (i.e. excluding withdrawals), n = 40

Usual TSH range (0.4–4.0 mU/L)

n = 21

Higher TSH range (4. 1–8.0 mU/L)

n = 19

Percent achieving target TSH range at week 12 (visit 2)

18/21 (85.7 %)

6/19 (31.6 %)

Percent achieving target TSH range at week 24 (visit 3)

18/21 (85.7 %)

10/19 (52.6 %)

Percent compliant at week 12 (visit 2)

21/21 (100 %)

18/19 (94.7 %)

Percent compliant at week 24 (visit 3)

21/21 (100 %)

18/19 (94.7 %)