Table 1 The median (5th–95th percentile range) values of clinical and laboratory parameters in patients with newly onset of thyrotoxicosis during pregnancy
Gestational thyrotoxicosis n = 30 | New onset Graves’ thyrotoxicosis during pregnancy n = 13 | p value** | |
|---|---|---|---|
Onset age (years) | 31.0 (24–40) | 33.0 (25–37) | 0.3257 |
Onset time (gestational weeks) | 12.0 (8–15) | 13.0 (10.8–17.8) | 0.018 |
FT4 (ng/dl) | 1.96 (1.61–2.52) | 2.47 (1.67–3.94) | 0.003 |
FT3 (pg/ml) | 4.67 (3.76–6.67) | 10.31 (4.72–30.00) | <0.001 |
FT3/FT4 | 2.38 (1.98–3.06) | 3.66 (2.40–7.47) | <0.001 |
Thyroid volume (g) | 17.1 (11.1–29.8) | 27.4 (17.8–40.8) | <0.001 |
Blood flow (%) | 1.6 (0.8–6.6) | 6.5 (1.4–18.8) | 0.004 |
TRAb (IU/l) | 1.3 (1.3–1.3)* | 5.6 (5.6–32.0) | <0.001 |
TgAb (IU/ml) | 28.0 (28.0–42.9)* | 28 (28–454.2)* | 0.003 |
TPOAb (IU/ml) | 16.0 (16.0–16.8)* | 19.3 (16–441.6)* | <0.01 |
Positive rate of TRAb (%) | 0 | 100 | <0.001 |
Positive rate of TgAb (%) | 10.0 | 46.2 | 0.007 |
Positive rate of TPOAb (%) | 3.3 | 46.2 | <0.001 |