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Table 1 Occurrence of complications of glucocorticoid therapy in patients with Graves’ orbitopathy (based on Marcocci et al., 2001 [9])

From: Life-threatening complications of high doses of intravenous methylprednisolone for treatment of Graves’ orbitopathy

 Oral (n = 27)Intravenous (n = 41)
Mild to moderate:
 Hyperglycemia, gain in body weight, depression, and Cushingoid features1727
Severe:
 Cardiovascular, cerebrovascular, > 4-fold increase in liver enzymes, acute liver failure, autoimmune hepatitis1014
  1. n number of physicians reporting adverse events