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Table 1 Occurrence of complications of glucocorticoid therapy in patients with Graves’ orbitopathy (based on Marcocci et al., 2001 [9])

From: Life-threatening complications of high doses of intravenous methylprednisolone for treatment of Graves’ orbitopathy

 

Oral (n = 27)

Intravenous (n = 41)

Mild to moderate:

 Hyperglycemia, gain in body weight, depression, and Cushingoid features

17

27

Severe:

 Cardiovascular, cerebrovascular, > 4-fold increase in liver enzymes, acute liver failure, autoimmune hepatitis

10

14

  1. n number of physicians reporting adverse events