Table 2 NICE guidelines on first line treatment for Graves’ disease in adults [5]

1.6.10

Offer radioactive iodine as first-line definitive treatment for adults with Graves’ disease, unless antithyroid drugs are likely to achieve remission (see recommendation 1.6.11), or it is unsuitable (for example, there are concerns about compression, malignancy is suspected, they are pregnant or trying to become pregnant or father a child within the next 4 to 6 months, or they have active thyroid eye disease).

1.6.11

Offer a choice of antithyroid drugs (a 12 to 18-month course) or radioactiveiodine as first-line definitive treatment for adults with Graves’ disease if antithyroid drugs are likely to achieve remission (for example, mild and uncomplicated Graves’ disease).

1.6.12

Offer antithyroid drugs (a 12 to 18 month course) as first-line definitive treatment for adults with Graves’ disease if radioactive iodine and surgery are unsuitable.