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Table 1 Thyroid hormone concentrations following administration of various combinations of massive doses of levothyroxine and triiodothyronine in order to “overcome” presumed malabsorption of levothyroxine

From: Adequate timing and constant supervision are the keys for successful implementation of levothyroxine or levothyroxine/paracetamol absorption test

Thyroid function tests (07.2017)

Date

Time

TSH [μIU/ml]

[Ref. Range 0.4–4.0]

FT4 [pmol/l]

[Ref. Range 11.5–22.7]

FT3 [pmol/l]

[Ref. Range 2.76–6.45]

Daily dose

p.o.

Day 1

10:00

> 75

4.12

3.06

LT4 1700 μg and T3 40 μg

18:00

nm*

3.99

3.16

2:00

nm

4.83

2.95

Day 2

10:00

nm

4.67

3.27

LT4 1700 μg and T3 40 μg

18:00

nm

4.35

3.24

2:00

nm

4.59

3.01

Day 3

18:00

nm

4.92

2.93

LT4 2200 μg and T3 40 μg

2:00

nm

4.38

2.87

Day 4

8:00

nm

6.38

2.86

LT4 3200 μg and T3 40 μg

18:00

nm

5.73

3.29

2:00

nm

5.78

3.55

Day 5

8:00

nm

5.96

2.93

LT4 3200 μg and T3 40 μg

Day 6

8:00

nm

6.64

3.9

LT4 3200 μg and T3 40 μg

Day 7

8:00

nm

6.96

3.62

LT4 3200 μg and T3 40 μg

Day 15

8:00

nm

6.62

3.81

LT4 1700 μg and T3 40 μg

Day 24

8:00

> 75

5.53

4.19

LT4 3000 μg

  1. *nm = not measured