TY - JOUR AU - Kihara, Minoru AU - Miyauchi, Akira AU - Masuoka, Hiroo AU - Higashiyama, Takuya AU - Ito, Yasuhiro AU - Miya, Akihiro PY - 2020 DA - 2020/07/21 TI - Kinetic analysis of the growth rate of sporadic and hereditary medullary thyroid carcinoma: comparing the postoperative calcitonin-doubling rate with the hypothetical preoperative tumor volume-doubling rate JO - Thyroid Research SP - 13 VL - 13 IS - 1 AB - Our previous kinetic analyses of changes in the tumor volume (TV) of papillary thyroid microcarcinomas during active surveillance revealed that the tumors’ growth varied over time from rather rapid growth to shrinkage and that the hypothetical TV-doubling rates (DRs) before the patients’ presentation were much larger than their observed TV-DRs, indicating that rapid growth phases preceded their presentation. Whether this phenomenon also occurs in medullary thyroid carcinoma (MTC) was unknown. SN - 1756-6614 UR - https://doi.org/10.1186/s13044-020-00087-6 DO - 10.1186/s13044-020-00087-6 ID - Kihara2020 ER -