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Table 1 Epidemiology of hyperthyroidism in GTD across various settings

From: Hyperthyroidism in gestational trophoblastic disease – a literature review

Study details

GTD type

Total number of GTD cases reviewed in study

Number of patients with hyperthyroidism

Authors

Year

Population and setting

Biochemical (% of total GTD cases)

Clinical (% of total GTD cases)

Walkington, et al. [11]

2011

Patients commencing chemotherapy for GTN at Weston Park hospital, Sheffield, United Kingdom, between January 2005 and January 2010.

GTN

196

14 (7.2)

4 (2)

Sun, et al. [12]

2016

Patients with CM and PM from the Trophoblastic disease centre, United States of America, between 1994 and 2013

CM

194

31 (16)

4 (2.1)

PM

172

8 (4.7)

4 (2.3)

Norman, et al. [13]

1981

Black patients with GTD admitted to the gynaecological wards of King Edward VIII Hospital, South Africa, over a 12-month period

GTN

27

15 (56)

9 (33)

Al Alaf, et al. [14]

2010

Patients with GTD admitted to Maternity Teaching Hospital, Erbil City, Iraq, from 1st October 2008 to 1st April 2009

GTN

3

10 (25) a

CM

33

  

PM

4

  

Bahasadri, et al. [15]

2011

Patients with CM or PM admitted to Akbarabadi Teaching Hospital, Tehran, Iran, between 21st June 1996 and 3rd July 2006

CM

230

10 (4.3) a

PM

34

0 (0) a

  1. aThere was no distinction between biochemical and clinical hypothyroidism in the study
  2. GTD Gestational trophoblastic disease
  3. GTN Gestational trophoblastic neoplasia
  4. CM Complete hydatidiform mole
  5. PM Partial hydatidiform mole