Table 2 Reported incidence of malignancy in all nodules including hot nodules and non-toxic nodules

Baser, H., et al. (2019) [22]

5

73

N/A

N/A

3.8

6.6

80 – Nondiagnostic

259 – Benign

17 – AUS/FLUS

2 – FN/SFN

2 – SM

4 - Malignant

8 – PTC

2 – FTC

3 – TTUMP

1 - UTC

Corrias, A., et al. (2010) [23]

30

16

11

6

22

16

3 suspicious

1 - PTC (All 3 suspicious FNAB were benign)

Derosa, G., et al. (1994) [24]

10

26

5

25

13

42

Not reported

8 - PTC

Dirikoc, A., et al. (2017) [25]

34

34

24

8

46

14

^a50 – Nondiagnostic

83 – indeterminate

13 – malignant

118 PTC 7 FTC 6 Other

Mon, S. Y., et al. (2018) [9]

13

12

33

100

8

8

2 - Benign

1 - AUS/FLUS

2 FTC (Both were FNAB benign)

Slijepcevic, N., et al. (2015) [26]

16

6

7

14

16

21

Not reported

9 PTC

Tam, A., et al. (2019) [27]

25

17

N/A

N/A

10

28

8 – Nondiagnostic

51 – Benign

3 – AUS/FLUS

2 – FN/SFN

1 - Malignant

10 PTC

4 FTC

(7 malignancies located outside hot nodule)