Skip to main content

Table 2 Ultrasound characteristics of Thy3 nodules

From: Prevalence of thyroid carcinoma in nodules with thy 3 cytology: the role of preoperative ultrasonography and strain elastography

Characteristics Overall Benign Thy3 Malignant Thy3 P - value† Odds ratio (95% confidence interval) Adjusted odds ratioa (95% confidence interval) p-value‡
Number of nodules 99 (100) 81 (81.81) 18 (18.18)     
Size
  ≤ 10 mm 61 (61.6) 50 (82.0) 11 (18.0) 0.96 Ref _  
  > 10 mm 38 (38.4) 31 (81.6) 7 (18.4)   1.03 (0.36, 2.93)  
 Size (mm) Median: 8.3 Median: 8.6 Median: 7.5 0.51 1.03 (0.94, 1.13) _  
IQR: 7.4 IQR: 7.2 IQR: 7.7    
 Solitary 6 (6.06) 5 (83.33) 1 (16.66) 0.92 Ref _  
 Multinodular 93 (93.93) 76 (81.72) 17 (18.28)   1.12 (0.12, 10.2)  
Nodule characteristics
 Solid hypoechoic 81 (81.81) 64 (79.01) 17 (20.99) 0.18 4.52 (0.56, 36.38)  
 Solid isoechoic 18 (18.18) 17 (94.44) 1 (5.55)   Ref   
Vascularity (color Doppler)
 Non vascular (no flow) 63 (63.63) 49 (77.8) 14 (22.2) 0.17 2.29 (0.69, 7.57)  
 Increased vascularity (peripheral and/or central flow) 36 (36.36) 33 (88.9) 3 (11.1)   Ref   
Margins
 Regular 85 (85.85) 72 (84.70) 13 (15.30) 0.02 4.56 (1.34, 15.48) 1.21 (0.16, 8.87) 0.86
 Irregular 14 (14.14) 9 (64.28) 5 (35.71)   Ref Ref  
Calcifications
 Yes 19 (19.19) 14 (73.68) 5 (26.31) 0.33 1.84 (0.57, 6.00)  
 No 80 (80.80) 67 (83.75) 13 (16.25)   Ref   
Ill-defined borders
 Yes 14 (14.14) 3 (21.42) 11 (78.58) ≤0.001 40.9 (9.2, 182.7) 27.88 (4.59, 169.37) 0.00
 No 85 (85.85) 78 (91.76) 7 (8.24)   Ref Ref
Taller than wide shape
 Yes 14 (14.14) 6 (42.85) 8 (57.15) ≤0.001 10.0 (2.87, 34.81) 4.80 (0.88, 26.19) 0.07
 No 85 (85.85) 75 (88.23) 10 (11.76)   Ref Ref  
  1. Variables are n (%) unless stated otherwise. †p-value from the χ2 test or Fisher’s exact test.
  2. p-value from the Mann-Whitney test.
  3. aAdjusted for margins, ill-defined borders, taller than wide shape, elastography and Thy3.
  4. p-value from multiple logistic regression.