|
Characteristics
|
Overall
|
Benign Thy3
|
Malignant Thy3
|
P - value†
|
Odds ratio (95% confidence interval)
|
Adjusted odds ratioa (95% confidence interval)
|
p-value‡
|
|---|
|
Number of nodules
|
99 (100)
|
81 (81.81)
|
18 (18.18)
| | | | |
|
Size
|
|
≤ 10 mm
|
61 (61.6)
|
50 (82.0)
|
11 (18.0)
|
0.96
|
Ref
|
_
| |
|
> 10 mm
|
38 (38.4)
|
31 (81.6)
|
7 (18.4)
| |
1.03 (0.36, 2.93)
| |
|
Size (mm)
|
Median: 8.3
|
Median: 8.6
|
Median: 7.5
|
0.51¶
|
1.03 (0.94, 1.13)
|
_
| |
|
IQR: 7.4
|
IQR: 7.2
|
IQR: 7.7
| | | |
|
Solitary
|
6 (6.06)
|
5 (83.33)
|
1 (16.66)
|
0.92
|
Ref
|
_
| |
|
Multinodular
|
93 (93.93)
|
76 (81.72)
|
17 (18.28)
| |
1.12 (0.12, 10.2)
| |
|
Nodule characteristics
|
|
Solid hypoechoic
|
81 (81.81)
|
64 (79.01)
|
17 (20.99)
|
0.18
|
4.52 (0.56, 36.38)
|
–
| |
|
Solid isoechoic
|
18 (18.18)
|
17 (94.44)
|
1 (5.55)
| |
Ref
| | |
|
Vascularity (color Doppler)
|
|
Non vascular (no flow)
|
63 (63.63)
|
49 (77.8)
|
14 (22.2)
|
0.17
|
2.29 (0.69, 7.57)
|
–
| |
|
Increased vascularity (peripheral and/or central flow)
|
36 (36.36)
|
33 (88.9)
|
3 (11.1)
| |
Ref
| | |
|
Margins
|
|
Regular
|
85 (85.85)
|
72 (84.70)
|
13 (15.30)
|
0.02
|
4.56 (1.34, 15.48)
|
1.21 (0.16, 8.87)
|
0.86
|
|
Irregular
|
14 (14.14)
|
9 (64.28)
|
5 (35.71)
| |
Ref
|
Ref
| |
|
Calcifications
|
|
Yes
|
19 (19.19)
|
14 (73.68)
|
5 (26.31)
|
0.33
|
1.84 (0.57, 6.00)
|
–
| |
|
No
|
80 (80.80)
|
67 (83.75)
|
13 (16.25)
| |
Ref
| | |
|
Ill-defined borders
|
|
Yes
|
14 (14.14)
|
3 (21.42)
|
11 (78.58)
|
≤0.001
|
40.9 (9.2, 182.7)
|
27.88 (4.59, 169.37)
|
0.00
|
|
No
|
85 (85.85)
|
78 (91.76)
|
7 (8.24)
| |
Ref
|
Ref
|
|
Taller than wide shape
|
|
Yes
|
14 (14.14)
|
6 (42.85)
|
8 (57.15)
|
≤0.001
|
10.0 (2.87, 34.81)
|
4.80 (0.88, 26.19)
|
0.07
|
|
No
|
85 (85.85)
|
75 (88.23)
|
10 (11.76)
| |
Ref
|
Ref
| |
- Variables are n (%) unless stated otherwise. †p-value from the χ2 test or Fisher’s exact test.
- ¶p-value from the Mann-Whitney test.
- aAdjusted for margins, ill-defined borders, taller than wide shape, elastography and Thy3.
- ‡p-value from multiple logistic regression.
