Table 2 Ultrasound characteristics of Thy3 nodules
Characteristics | Overall | Benign Thy3 | Malignant Thy3 | P - value† | Odds ratio (95% confidence interval) | Adjusted odds ratioa (95% confidence interval) | p-value‡ |
|---|---|---|---|---|---|---|---|
Number of nodules | 99 (100) | 81 (81.81) | 18 (18.18) | ||||
Size | |||||||
≤ 10 mm | 61 (61.6) | 50 (82.0) | 11 (18.0) | 0.96 | Ref | _ | |
> 10 mm | 38 (38.4) | 31 (81.6) | 7 (18.4) | 1.03 (0.36, 2.93) | |||
Size (mm) | Median: 8.3 | Median: 8.6 | Median: 7.5 | 0.51¶ | 1.03 (0.94, 1.13) | _ | |
IQR: 7.4 | IQR: 7.2 | IQR: 7.7 | |||||
Solitary | 6 (6.06) | 5 (83.33) | 1 (16.66) | 0.92 | Ref | _ | |
Multinodular | 93 (93.93) | 76 (81.72) | 17 (18.28) | 1.12 (0.12, 10.2) | |||
Nodule characteristics | |||||||
Solid hypoechoic | 81 (81.81) | 64 (79.01) | 17 (20.99) | 0.18 | 4.52 (0.56, 36.38) | – | |
Solid isoechoic | 18 (18.18) | 17 (94.44) | 1 (5.55) | Ref | |||
Vascularity (color Doppler) | |||||||
Non vascular (no flow) | 63 (63.63) | 49 (77.8) | 14 (22.2) | 0.17 | 2.29 (0.69, 7.57) | – | |
Increased vascularity (peripheral and/or central flow) | 36 (36.36) | 33 (88.9) | 3 (11.1) | Ref | |||
Margins | |||||||
Regular | 85 (85.85) | 72 (84.70) | 13 (15.30) | 0.02 | 4.56 (1.34, 15.48) | 1.21 (0.16, 8.87) | 0.86 |
Irregular | 14 (14.14) | 9 (64.28) | 5 (35.71) | Ref | Ref | ||
Calcifications | |||||||
Yes | 19 (19.19) | 14 (73.68) | 5 (26.31) | 0.33 | 1.84 (0.57, 6.00) | – | |
No | 80 (80.80) | 67 (83.75) | 13 (16.25) | Ref | |||
Ill-defined borders | |||||||
Yes | 14 (14.14) | 3 (21.42) | 11 (78.58) | ≤0.001 | 40.9 (9.2, 182.7) | 27.88 (4.59, 169.37) | 0.00 |
No | 85 (85.85) | 78 (91.76) | 7 (8.24) | Ref | Ref | ||
Taller than wide shape | |||||||
Yes | 14 (14.14) | 6 (42.85) | 8 (57.15) | ≤0.001 | 10.0 (2.87, 34.81) | 4.80 (0.88, 26.19) | 0.07 |
No | 85 (85.85) | 75 (88.23) | 10 (11.76) | Ref | Ref | ||