Table 1 Association between transient congenital hypothyroidism (CH) and potential risk factors
| Variable |
Control N = 340 |
Transient CH N = 204 | OR (95% CI) | P value* |
|---|---|---|---|---|
| Gestational age (week) | ||||
| ≤ 37 | 310 | 153 | 3.44 (2.1–5.62) | 0.001 |
| > 37 | 30 | 51 | 1 | |
| Birth length (cm) | ||||
| ≤ 50 | 100 | 53 | 1.18 (0.8–1.75) | 0.223 |
| > 50 | 240 | 151 | 1 | |
| Parental consanguineous marriage | ||||
| No | 296 (87.1) | 161 (78.9) | 1 | 1 |
| Yes | 44 (12.9) | 43 (21.1) | 2.17 (1.57–3) | 0.001 |
| Betadine usage | ||||
| No | 336 (98.2) | 191 (93.6) | 1 | 1 |
| Yes | 4 (1.2) | 13 (6.4) | 5.62 (1.8–17.5) | 0.003 |
| Gender | ||||
| Male | 181 (53.2) | 109 (53.4) | 1 | 1 |
| Female | 159 (46.8) | 95 (46.6) | (0.72–1.4) | 0.97 |
| History of CH in the first degree | ||||
| No | 335 (98.5) | 188 (92.2) | 1 | 1 |
| Yes | 5 (1.5) | 16 (7.8) | 5.6 (2.02–15.5) | 0.001 |
| Neonatal jaundice | ||||
| No | 299 (87.9) | 141 (69.1) | 1 | 1 |
| Yes | 41 (12.1) | 63 (30.9) | 3.53 (2.26–5.51) | 0.001 |
| Birth weight (gr) | ||||
| < 2500 | 19 (5.6) | 23 (11.3) | 1 | 1 |
| 4000–2500 | 308 (90.6) | 174 (85.3) | 0.39 (0.22–0.69) | 0.01 |
| > 2500 | 13 (3.8) | 7 (3.4) | 0.39 (0.15–1.3) | 0.058 |
| Mother’s age (year) | ||||
| < 20 | 43 (12.6) | 22 (10.8) | 1 | 1 |
| 20–30 | 97 (28.5) | 77 (37.7) | 1.6 (0.89–2.94) | 0.1 |
| 30–40 | 127 (37.4) | 78 (38.2) | 1.2 (0.36–1.42) | 0.54 |
| > 40 | 73 (21.5) | 27 (13.2) | 0.74 (0.78–1.45) | 0.34 |