Table 1 PICOS criteria for inclusion and exclusion of studies
Inclusion criteria | Exclusion criteria | |
|---|---|---|
Population | Pregnant women and their children. | Studies including women of childbearing age but not during pregnancy and/or post-natally will be excluded. |
Intervention | Assessment of dietary contributors to iodine status during pregnancy and neurodevelopment outcomes in offspring including natural dietary sources and “accidental” supplementation e.g., women taking supplement prior to/not as part of the study. | Any articles involving intentional dietary supplementation of iodine will be excluded. |
Comparison | Pregnant women with low iodine status during pregnancy and/or associations with neurodevelopment in offspring. | Studies that have no detail on iodine status and/or cognitive outcomes during pregnancy on offspring. |
Outcomes | The main dietary contributors to iodine status during pregnancy and/or associations with neurodevelopment in offspring. | Studies that did not measure child cognitive/neurodevelopment outcomes and/or detail urinary iodine measurements or dietary data. |
Study Design | All study types e.g., Prospective Cohort, Observational studies, and cross-sectional studies. | Animal study, in vitro study, drug study, chemical interaction study, laboratory study, food technology study, cell culture study, method development paper, Fortification studies, Supplementation trials, research policy/ policy making, proof of concept, letters, editorials, systematic reviews and meta-analyses, commentaries, studies not published in the English language. |