Skip to main content

Table 1 Detection and characterization of interference using polyethylene glycol, heterophilic blocking tube, and streptavidin-coated magnetic particle SA-MP treatment

From: Falsely diagnosed thyrotoxicosis caused by anti-streptavidin antibodies and pre-wash procedures

 

TSH, μIU/mL (RR: 0.50–5.00)

FT4, ng/dL (RR: 0.90–1.70)

FT3, pg/mL (RR: 2.3–4.0)

Patient

 Before PEG Tx

4.67

2.66

5.88

 After PEG Tx (actual measured value)

4.77

0.87

2.11

 After PEG Tx (calculated value)

9.54

–

–

 

TSH

FT4

FT3

 Recovery (%)

204 (RR: 30–80)

33 (RR: 60–90)

36 (RR: 60–90)

 

TSH, μIU/mL (RR: 0.50–5.00)

FT4, ng/dL (RR: 0.90–1.70)

FT3, pg/mL (RR: 2.3–4.0)

Patient

 Before HBT Tx or SA-MP Tx

4.36

2.15

4.27

 After HBT Tx

6.49

1.68

3.86

 After SA-MP Tx

9.81

1.04

2.7

Control

 Before HBT Tx and SA-MP Tx

3.65

1.63

3.62

 After HBT Tx

3.69

1.64

3.64

 After SA-MP Tx

3.64

1.66

3.61

  1. PEG Tx resulted in a high TSH level but low FT4 and FT3 recovery. HBT Tx or SA-MP Tx resulted in a higher TSH but lower FT4 and FT3 values. However, HBT Tx or SA-MP Tx showed almost the same results in the control sample