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Table 2 Thyroid function test parameters as measured by different immunoassays (Elecsys and Architect)

From: Falsely diagnosed thyrotoxicosis caused by anti-streptavidin antibodies and pre-wash procedures

 

Elecsys

Architect

Cobas8000 e602 (with pre-wash)

Cobas e411(without pre-wash)

Patient

 TSH, μIU/mL

4.36 (RR: 0.50–5.00)

4.77 (RR: 0.50–5.00)

8.57 (RR: 0.35–4.94)

 FT4, ng/dL

2.15 (RR: 0.90–1.70)

1.31 (RR: 0.90–1.70)

0.86 (RR: 0.70–1.48)

 FT3, pg/mL

4.27 (RR: 2.3–4.0)

3.66 (RR: 2.3–4.0)

2.44 (RR: 1.71–3.71)

  1. Cobas8000 e602, which is performed with pre-washing, resulted in almost the same level of TSH and with higher FT4 and FT3 values compared to Cobas e411, which is not performed with pre-wash. Architect provided the highest TSH level and lowest FT4 and FT3 values among the three instruments
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Thyroid Research

ISSN: 1756-6614