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Table 1 Differences between IC50 values of BI-847325 in 2D and 3D ATC cell culture systems

From: Alginate-based 3D cell culture technique to evaluate the half-maximal inhibitory concentration: an in vitro model of anticancer drug study for anaplastic thyroid carcinoma

Cell lines

Hours

IC50

 
  

2D

3D

C643

24

3 μM

25 μM

48

2 μM

15 μM

72

2 μM

15 μM

SW1736

24

5 μM

43 μM

48

4 μM

34 μM

72

4 μM

34 μM