Skip to main content

Table 1 Some clinical and thyroidal data evaluated. The numbers of women in whom the given parameters were available are reported in brackets. Comparison was made between women with normal thyroid function and women on L-T4 therapy. Other drugs were: spironolactone (n = 2), dopamine-antagonist (n = 2), steroids (n = 2), rizatriptan (n = 1), and hydroxychloroquine (n = 1)

From: Evaluation of anti-Müllerian hormone in pre-menopausal women stratified according to thyroid function, autoimmunity and age

  All women (n = 250) Women with normal thyroid function (n = 171) Women on L-T4 therapy (n = 79) Significance
P
Age (year); mean ± SD 34.1 ± 9.9 31.5 ± 9.2 39.7 ± 9.5 < 0.0001
BMI (kg/m2); median, IQR, Cl 22.2; 20.2-25.6
21.5-22.9
21.7; 19.9-25.2
21.1-22.6
23.5; 21.2-26.6
21.9-22.4
0.03
Non-smokers (%) 71% (116) 72% (90) 54% (26) 0.01
Former/current smokers (%) 29% (47) 28% (25) 46% (22)  
TSH (mIU/l); median, IQR, Cl 2.00; 1.28-2.84
1.84-2.23
2.08; 1.35-2.83
1.87-2.30
1.84; 1.05-2.85
1.48-2.17
0.11
f-T4 (pmol/l); median, IQR, Cl 13.4; 11.5-15.7
13.0-14.0
12.9; 11.1-14.7
12.4-13.3
15.2; 12.8-17.6
14.0-16.2
< 0.0001
L-T4 (μg/day); median, IQR, Cl 60.0; 50.0-90.7
57.1-75.0
 
TPOAb positive (%) 43% (166) 20% (96) 66% (70) < 0.0001
TV (ml); median, IQR, Cl 7.9; 6.4-10.6 (215) 7.4-8.4 7.9; 6.6-10.3 (151) 7.6-8.5 8.0; 5.4-12.1 (64) 6.2-9.5  
Other ongoing drugs (number) none 124 91 33  
vitamin D/other vitamins 27 14 13  
hormonal contraceptives 28 21 7  
psychotropic drugs 23 13 10  
cabergoline 17 13 4  
metformin 8 6 2  
anti-secretive drugs 7 2 5  
H1- inhibitors drugs 5 4 1  
statins 3 2 1  
other drugs 8 7 1