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Table 2 Factors associated with time to failure in patients receiving ATD with univariable and multivariable cox regression analysis

From: Incidence and treatment outcomes of Graves’ disease in Thailand: a single-center retrospective observational study

Factors

Univariate

p-value

HR (95% CI)

Multivariate

p-value

HR (95% CI)

Sex

 Female

0.56

0.91 (0.67–1.25

  

Male

Age

  < 40y

  ≥ 40y

0.39

1.15 (0.84–1.56

  

GO

 Present

0.01

1.83 (1.13–2.95)

0.024*

1.76 (1.08–2.88)

Absent

TSH

  < 0.01 uIU/ml

0.005

1.64 (1.16–2.33

0.007*

1.61 (1.14–2.28)

  ≥ 0.01 uIU/ml

FT3

  ≤ 3UNL

  > 3UNL

0.44

0.9 (0.72–1.33)

  

FT4

  ≤ 3UNL

  > 3UNL

0.3

0.84 (0.6–1.17)

  

TPP

 Present

0.58

0.83 (0.42–1.62

  

Absent

AF

 Present

0.06

1.56 (0.99–2.45

  

Absent

Severe disease

 Present

0.52

0.84 (0.49–1.43

  

Absent

  1. GO Graves Orbitopathy, UNL Upper normal limit, TPP Thyrotoxic periodic paralysis, AF Atrial fibrillation