Fig. 2
From: Targeted therapy with vemurafenib in BRAF(V600E)-mutated anaplastic thyroid cancer
A Pleomorphic tumor cells with intermixed tumor giant cells with prominent nucleoli arranged in a loose pattern with admixed inflammatory cells. B The tumor cells reveal a variable expression of keratin 18. C TTF1 is detected in tumor cell nuclei. D Tumor cells are positive after incubation with a mutation specific BRAFV600 antibody. Note, negativity of admixed inflammatory cells. Original magnification each 200-fold