TSH receptor antibodies have predictive value for breast cancer – retrospective analysis

Table 3 Hormone and autoantibody concentrations as determinants of breast cancer or benign breast tumors

Parameter	Association with BC (n = 9)						Association with BBT (n = 47)
	Univariate logistic regression			Multivariate logistic regression			Univariate logistic regression
	OR	95% CI	p	OR	95% CI	p	OR	95% CI	p
TSH (mIU/L)	0.97	0.75-1.26	ns	-			1.20	0.92-1.55	ns
FT ₄ (ng/dL)	0.96	0.42-2.21	ns				1.01	0.78-1.31	ns
FT ₃ (pg/mL)	0.48	0.71-1.82	ns				0.95	0.81-1.11	ns
TSHRAb (IU/mL)	1.10	1.01-1.20	0.0222	0.92	0.66-1.28	ns	0.97	0.91-1.03	ns
TgAb (IU/mL)	1.00	1.00-1.01	0.0377	0.99	0.99-1.00	ns	1.00	0.99-1.00	ns
TPOAb (IU/mL)	1.00	0.99-1.01	ns	-			1.00	0.99-1.00	ns

Univariate and multivariate logistic regression analysis of the univariate determinants (such as hormone and autoantibody concentrations) of breast cancer (BC) or breast benign tumor (BBT), performed in all patients (n = 1686); OR, odds ratio; CI, confidence interval; ns, non-significant.

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